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The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity.

Authors :
Rodriguez-Esteban, Concepcion
Tsukui, Tohru
Yonei, Sayuri
Magallon, Jorge
Tamura, Koji
Belmonte, Juan Carlos Izpisua
Source :
Nature. 4/29/1999, Vol. 398 Issue 6730, p814. 5p. 48 Color Photographs.
Publication Year :
1999

Abstract

Presents research which showed that the T-box genes Tbx4 and Tbx5 are regulators of limb outgrowth in chicks. Genes associated with fibroblast growth factor (FGF), bone morphogenic protein (BMP), and Wnt; Role of Pitx1 genes in embryonic development; Control of limb identity by Tbx4 and Tbx5.

Details

Language :
English
ISSN :
00280836
Volume :
398
Issue :
6730
Database :
Academic Search Index
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
1832489
Full Text :
https://doi.org/10.1038/19769