Cyclic mechanical strain-induced proliferation and migration of human airway smooth muscle cells: role of EMMPRIN and MMPs.

Presents findings of a study which determined the role of the mechanical strain of human airway smooth muscle (HASM) cells in inducing their proliferation and migration. Contribution of matrix metalloproteinases (MMP) to strain-induced HASM proliferation and migration; Integration of extracellular matrix metalloproteinase inducer within HASM cells; Role of MMP in HASM cell migration and invasion; Effect of cyclic strain of HSM on Tenascin-C release.