Back to Search
Start Over
Contemporary Incidence of Cognitive Impairment or Dementia in Patients Undergoing Coronary Artery Bypass Grafting: A Systematic Review and Meta-Analysis.
- Source :
-
Dementia & Geriatric Cognitive Disorders . 2025, Vol. 54 Issue 1, p52-66. 15p. - Publication Year :
- 2025
-
Abstract
- Introduction: Despite the high prevalence of cognitive impairment or dementia post-coronary artery bypass grafting (CABG), the incidence of cognitive impairment or dementia post-CABG in contemporary practice is currently unclear. Therefore, this paper aims to investigate the incidence and associated risk factors of cognitive impairment or dementia in patients' post-CABG. Methods: A systematic search across three databases (PubMed, SCOPUS, and Embase) was conducted for studies published in or after 2013 that reported cognitive impairment or dementia post-CABG. Subgroup analyses and meta-regression by risk factors were performed to determine their influence on the results. Results: This analysis included 23 studies with a total of 2,620 patients. The incidence of cognitive impairment or dementia less than 1 month, 2 to 6 months, and more than 12 months post-CABG was 35.96% (95% confidence interval [CI]: 28.22–44.51, I2 = 87%), 21.33% (95% CI: 13.44–32.15, I2 = 88%), and 39.13% (95% CI: 21.72–58.84, I2 = 84%), respectively. Meta-regression revealed that studies with more than 80% of the cohort diagnosed with hypertension were significantly associated with incidence of cognitive impairment or dementia less than 1 month post-CABG. Conclusion: This meta-analysis demonstrates a high incidence of cognitive impairment or dementia in patients' post-CABG in contemporary practice, particularly less than 1 month post-CABG and more than 12 months post-CABG. We found that hypertension was a significant risk factor in the short-term (less than 1 month) follow-up period for cognitive impairment or dementia post-CABG. Future research should be done to assess strategies to reduce cognitive impairment post-CABG. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DEMENTIA risk factors
*COGNITION disorder risk factors
*RISK assessment
*MEDICAL information storage & retrieval systems
*SURGERY
*PATIENTS
*RESEARCH funding
*META-analysis
*DESCRIPTIVE statistics
*CORONARY artery bypass
*SURGICAL complications
*SYSTEMATIC reviews
*MEDLINE
*COGNITION disorders
*DEMENTIA
*ONLINE information services
Subjects
Details
- Language :
- English
- ISSN :
- 14208008
- Volume :
- 54
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Dementia & Geriatric Cognitive Disorders
- Publication Type :
- Academic Journal
- Accession number :
- 182846999
- Full Text :
- https://doi.org/10.1159/000540450