Technical validation of controlled exposure to cat dander in the specialized particulate control environmental exposure unit (SPaC-EEU).

The document discusses the technical validation of controlled exposure to cat dander in the Specialized Particulate Control Environmental Exposure Unit (SPaC-EEU) located in Kingston, Canada. The SPaC-EEU, a micro-controlled room within the Environmental Exposure Unit, has been successfully validated for use with house dust mites and now cat dander. The study utilized specialized equipment to distribute cat allergen consistently throughout the facility, with the Laser Particle Counter (LPC) proving to be an effective method for real-time monitoring of Fel d 1 concentrations. This validation paves the way for future clinical studies with human participants in the SPaC-EEU. [Extracted from the article]