A streamlined and authenticated GC-MS method for the simultaneous analysis of all regulated chlorinated organic carriers (COCs) from the consumer goods at ng mL−1 level.

AbstractThis study presents a novel approach for the simultaneous identification and quantification of extractable chlorinated organic carriers (COCs) from diverse materials, including textiles, foam and leather. COCs, valued for chemical synthesis, dye transfer and solvents for dye formulations. In this work, dichloromethane under ultrasonic conditions at 25 °C for 30 minutes was employed for the extraction of COCs. Gas chromatography mass spectrometry (GC-MS) utilizing a DB-5MS column facilitated the separation and detection of target analytes. SIM ionization mode was utilized with target and qualifier ions for detection. Optimization of parameters such as extractant type, extraction method, and time resulted in high recoveries ranging from 95% to 105%. The calibration curve exhibited a range of 5 to 120 ng mL−1 with regression values of 0.996–0.998. The method demonstrated excellent precision with relative standard deviations (RSD) below 10% for test specimens and for pure standards. Limits of detection (LODs) was below 0.1 ng mL−1, indicating high sensitivity. Application of the developed method to real specimens successfully detected COCs at concentrations ranging from 2.60 to 9.94 ng mL−1, affirming its effectiveness in environmental monitoring and risk assessment. [ABSTRACT FROM AUTHOR]