MMP-8 与口腔疾病关系的研究进展.

Matrix metalloproteinase-8 (MMP-8), as an important member of MMPs family, undergoes activation through cysteine transformation mechanism in the presence of inflammation and reactive oxygen species, and finally changes from inactive form to active form to play a pathogenic role. Numerous studies have shown that the overexpression and release of MMP-8 can cause common oral diseases, such as dental caries, periodontal tissue damage and peri-implantitis. This article aimed to review the effect of MMP-8 in oral diseases, understand the mechanism of MMP-8,and provided potential targets and therapeutic ideas for the clinical treatment of oral diseases. [ABSTRACT FROM AUTHOR]