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肠道菌群及其代谢产物在动脉粥样硬化发生发展中的作用.

Authors :
王艾云
王雨婷
蔡静
倪若妍
罗彩莹
喻卓
陈鹏
Source :
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao. 2024, Vol. 45 Issue 12, p160-166. 7p.
Publication Year :
2024

Abstract

Intestinal flora and their metabolites play an important role in the occurrence and development of cardiovascular diseases such as atherosclerosis (AS), and have become an important target for the prevention and treatment of AS. In this paper, we focus on the intestinal microecological environment and focus on the relationship between intestinal flora metabolites such as trimethylamine oxide (TMAO), short-chain fatty acids (SCFA), phenylacetylglutamine (PAG), lipopolysaccharides (LPS), and bile acids (BA), and AS. At the same time, we also discuss the therapeutic strategies of AS that start from adjusting the intestinal flora and its metabolites, with the hope of opening up a new avenue of AS prevention and treatment. We hope to open up new avenues for the prevention and treatment of AS. [ABSTRACT FROM AUTHOR]

Details

Language :
Chinese
ISSN :
2095610X
Volume :
45
Issue :
12
Database :
Academic Search Index
Journal :
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao
Publication Type :
Academic Journal
Accession number :
182416311
Full Text :
https://doi.org/10.12259/j.issn.2095-610X.S20241223