Evaluating clinical utility of comprehensive genomic profiling—challenges and opportunities.

The article discusses the challenges and opportunities in evaluating the clinical utility of comprehensive genomic profiling in cancer precision medicine. It highlights the complexities of regulatory and reimbursement processes for these tests, as well as the importance of evidence-based decision-making. The study by Stackland et al. focuses on assessing the peer-reviewed literature related to the clinical utility of a specific genomic profiling platform, providing insights into the levels of evidence required for efficacy evaluation. The article emphasizes the need for generating high-quality evidence to establish the clinical utility of comprehensive genomic profiling and suggests better ways to assess its benefits and risks in guiding treatment decisions. [Extracted from the article]