Substituted piperidine challenge: Substituted piperidine challenge: Kozytskyi and Tymoschuk.

The article in the "Analytical & Bioanalytical Chemistry" journal presents a challenge focused on the NMR spectra of substituted piperidines, which are important in natural products and biologically active compounds. Participants are asked to distinguish between cis and trans isomers of 3,4-disubstituted piperidines using only the g-HSQC NMR spectra provided. The challenge aims to test knowledge in analytical chemistry and offers a prize for the randomly selected winner. Readers are encouraged to participate by submitting their solutions by a specified deadline. [Extracted from the article]