CD34+ progenitor cells meet metrology.

The document discusses the measurement of CD34+ hematopoietic progenitor cells (HPC) using flow cytometry, emphasizing the importance of accurate quantification due to its clinical impact. It highlights the challenges in determining measurement uncertainty and total error for CD34+ cells, especially in the context of HPC transplantation. The study by Fernández-Luis and colleagues attempts to define the allowable total error for CD34+ cell counting, showing variability in misclassification risk and the need for continuous improvement in analytical performance. The document concludes that standardized procedures and stabilized samples can enhance the accuracy of CD34+ cell enumeration, contributing to compliance with quality standards. [Extracted from the article]