Routine oxygen heterocyclic compounds analysis of fragrances using an eco-friendly liquid chromatography coupled to tandem mass spectrometry method.

Coumarin and furocoumarins characterization in cosmetics plays an important role in protecting consumer health. The analytical technique mostly employed for the analysis of these molecules is certainly liquid chromatography coupled to photodiode array or mass spectrometer detectors. The aim of this article was to investigate on the oxygen heterocyclic compounds content in fifty hydro alcoholic fragrances using a fast, sensitive and eco-friendly liquid chromatography coupled to a triple quadrupole mass spectrometer detector analytical method without any sample pre-treatment. To the best of the author's knowledge, this is the first research article on the quantification of thirty-six oxygen heterocyclic compounds in hydro alcoholic fragrances in less than 4 min and with the use of water/ethanol as mobile phase. Thanks to the good performance of the analytical method used, this can be proposed among the routine methods for the quality control of cosmetics and finished products. [ABSTRACT FROM AUTHOR]