Research progress on pathogenicity and immune response mechanism of Salmonella infected poultry.

Salmonella can cause infection in poultry and lead to intestinal lesions, and food-borne infections in humans through food transmission. Salmonella enters the intestines of poultry through oral ingestion, adheres to and invades intestinal epithelial cells, uses M cells and macrophages to achieve intracellular survival and reproduction, and causes intestinal lesions and systemic invasion. Virulence genes and plasmids are regulated during this process, including SPI-1 and SPI-2 encoded type IE secretion systems and induced filamentous formation that help bacteria evade host defenses. Birds enhance their ability to clear Salmonella by regulating the synergistic effect of innate immune system and adaptive immune system. In this paper, the etiology, transmission route, pathogenesis and immune response mechanism of Salmonella were described, in order to provide reference for further study of Salmonella infection in poultry. [ABSTRACT FROM AUTHOR]