Genetics Corner: Caudal Limb-like Appendage with Complex Spinal Dysraphism in a Newborn with a Likely Pathogenic Variant in ACTB.

The article focuses on a case involving a 6-year-old girl with complex genetic anomalies, including a caudal limb-like appendage and spinal dysraphism. Topics include the identification of a likely pathogenic variant in Actin Beta (ACTB), its connection to Baraitser-Winter syndrome, and the patient's development of a limb-like appendage due to spinal dysraphism.