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Genetic variants explain ancestry‐related differences in type 2 diabetes risk.

Authors :
Deutsch, Aaron J.
Smith, Kirk
Udler, Miriam S.
Source :
Clinical & Translational Medicine. Nov2024, Vol. 14 Issue 11, p1-3. 3p.
Publication Year :
2024

Abstract

The article discusses how genetic variants play a role in explaining the differences in type 2 diabetes risk among individuals of different ancestries. By utilizing large-scale genome-wide association studies, researchers have identified genetic clusters associated with beta cell dysfunction, insulin resistance, and other clinical phenotypes related to type 2 diabetes. The study specifically focuses on differences between European and East Asian populations, highlighting how genetic variations can impact disease risk and the need for personalized approaches to managing type 2 diabetes based on genetic information. The findings underscore the potential of genetic data in understanding disease mechanisms and developing tailored strategies for diagnosis and treatment. [Extracted from the article]

Details

Language :
English
ISSN :
20011326
Volume :
14
Issue :
11
Database :
Academic Search Index
Journal :
Clinical & Translational Medicine
Publication Type :
Academic Journal
Accession number :
181439950
Full Text :
https://doi.org/10.1002/ctm2.70076