High-throughput screening of gold nanoparticle synthesis parameters in droplet microfluidics.

[Display omitted] A 3D printed microreactor and UV-VIS spectral diagnostic system were adapted for an automatic protocol for screening parameters of citrate-based droplet synthesis of gold nanoparticles. Using this system, 27 combinations of synthesis parameters were screened within an hour and data were collected from more than 1000 individual droplets with nanoparticles. The developed system allows both filtering the spectra of target droplets and conducting a comprehensive multivariate analysis of all key descriptors. [ABSTRACT FROM AUTHOR]