Chemical profiling and bioactivity analysis of shoots and roots essential oil of Indian Blumea mollis (D. Don) Merr.

Aromatic plants contain essential oils, potent extracts renowned for therapeutic benefits. Essential oils are commonly utilized due to their diverse range of phytochemicals that possess therapeutic properties. The present study analyses the chemical composition of the essential oil obtained from shoots and roots of Blumea mollis (Family: Asteraceae), using GC-FID and GC-MS techniques. A total of 49 and 46 compounds were identified from shoots and roots accounting for 95.6 % and 88.4 % respectively. β-caryophyllene is reported as major compound 36.2 ± 0.50 % in essential oil of the shoots and 33.8 ± 0.55 % in essential oil of the roots. Both essential oils of shoots and roots were dominated by sesquiterpene hydrocarbons (59.2–76.4%), followed by oxygenated sesquiterpene (14.9–20.3%). The in vitro antioxidant activity was determined using DPPH radical scavenging activity, H 2 O 2 radical scavenging activity, and Iron(II) complexing activity. The highest antioxidant activity was observed in root essential oil of B. mollis. The oils also inhibited the activity of α-amylase with IC 50 of 3.53 ± 0.04 μg/ml (shoot), 3.45 ± 0.04 μg/ml (root). Root oil also showed good activity for protein denaturation with IC 50 of 3.02 ± 0.03 g/ml as compared to shoot essential oil. This is first time that essential oil constituent and biological activity of B. mollis roots and shoots have been characterized from India. [Display omitted] • This is the first report about chemical composition analysis of shoots and roots essential oil of Blumea mollis. • The roots of B. mollis show high essential oil yield than aerial part. • Chemical composition analysis of essential oil was done by using GC-FID and GC-MS techniques. • Biological activity analysis confirms potent in-vitro antioxidant, inhibition of α-amylase, and inhibition of protein denaturation activities in essential oil. • This study provides an overview about both shoot and root essential oil composition of B. mollis. [ABSTRACT FROM AUTHOR]