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Malignant meningioma of the falx cerebri in a child: case report and literature review.

Authors :
Guo, Rongzeng
Yan, Changxiang
Fu, Xiaojun
Source :
Child's Nervous System. Dec2024, Vol. 40 Issue 12, p4295-4300. 6p.
Publication Year :
2024

Abstract

Meningiomas are common intracranial tumors in adults but rare in pediatric cases, with malignant histological features being even less frequent. Primary pediatric malignant meningioma of the falx cerebri has not been previously reported in the literature. We present a case of a malignant meningioma of the falx cerebri in a child who was admitted to the hospital following head trauma, presenting with mental impairment and limb weakness. CT examination revealed a right parietal epidural hematoma and a large intracranial lesion. The patient underwent drainage of the intracranial hematoma and a two-frontal craniotomy with tumor resection under microscopy. Histopathological analysis confirmed malignant meningioma, and genetic testing identified a YAP1-MAML2 gene fusion. There is no consensus on the clinical, imaging, and pathological features of pediatric meningiomas. In this paper, we discuss the clinical features, diagnostic and treatment protocols, and pathological characteristics of this case, along with a review of the relevant literature. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
02567040
Volume :
40
Issue :
12
Database :
Academic Search Index
Journal :
Child's Nervous System
Publication Type :
Academic Journal
Accession number :
180991075
Full Text :
https://doi.org/10.1007/s00381-024-06600-8