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Catalytic Enantioselective Functionalization of Maleimides: An Update.

Authors :
Amatore, Muriel
Bonne, Damien
Constantieux, Thierry
Rodriguez, Jean
Source :
Chinese Journal of Chemistry. Dec2024, Vol. 42 Issue 24, p3605-3622. 18p.
Publication Year :
2024

Abstract

Comprehensive Summary: Maleimide derivatives are well‐established reactive intermediates also found in natural products, synthetic pharmaceuticals and functional polymers. Their specific reactivity found widespread applications in the field of bioconjugation and allowed for the development of highly selective functionalizations based on simple additions and cycloadditions with the possible control of central and C–N axial chirality. These multisite‐reactive scaffolds have aroused a long‐standing interest throughout the scientific community more particularly as powerful electrophilic partners and more recently as nucleophilic partners in some specific transformations. The persistent interest in these easily accessible synthetic platforms over the last decade has enabled the development of new enantioselective transformations and the major advancements in this field are presented in this review. Key Scientists: [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1001604X
Volume :
42
Issue :
24
Database :
Academic Search Index
Journal :
Chinese Journal of Chemistry
Publication Type :
Academic Journal
Accession number :
180925009
Full Text :
https://doi.org/10.1002/cjoc.202400787