Efficacy and Safety of Carbapenem Antibiotics in Hidradenitis Suppurativa: A Systematic Review.

The systematic review titled "Efficacy and Safety of Carbapenem Antibiotics in Hidradenitis Suppurativa" explores the use of carbapenem antibiotics in treating the chronic inflammatory skin disorder, Hidradenitis Suppurativa (HS). The study included 181 patients with HS who received carbapenem treatment, primarily ertapenem, showing clinical improvement and pain reduction. Minor adverse events were reported, and consolidation therapy post-carbapenem treatment was beneficial in maintaining clinical improvement. The review suggests the potential utility of carbapenems in treating recalcitrant HS, but highlights the need for further large-scale clinical trials to optimize treatment strategies. [Extracted from the article]