Micro vascularization of Human Fetal Kidney: An Observational Study.

Introduction: Micro vasculature of kidney undergoes a continual and mutually dependent developmental changes through which obtains its structural and functional maturity. It is very important to know the normal developmental anatomy of kidney micro vasculature in prenatal diagnosis of renal anomalies, genetic counseling and treatment of prenatal renal disorders like Wilm’s tumor, multicystic renal dysplasia. Present study was undertaken to study the micro vasculature of the kidney at different stages of development during fetal life. Materials And Method: The present study was carried out in the department of Anatomy, Regional Institute of Medical Sciences, Imphal, Manipur. The material for the study consisted of 60 spontaneously aborted and still born human fetal specimens free from any gross congenital anomalies with gestational age between 11th to 38thweeks were collected from Obstetrics and Gynaecology department, RIMS after taking permission from the Institutional Ethics Committee and categorized into 4 groups as Group-A(11-20 weeks), Group-B(21-27 weeks),Group- C(28-33 week), Group-D(34-38 weeks) .The kidneys were taken out from fetal specimens, fixed, processed, stained with Haematoxylin and Eosin, observed under the Microscope and micro photographed. Conclusion: Knowledge on microvascular development on fetal kidney will be helpful for possible intervention in prematurely delivered normal baby with possible prognosis as premature delivery is very common now a days and also in prenatal diagnosis of kidney diseases. [ABSTRACT FROM AUTHOR]