Control of Hypotension During Spinal Anaesthesia for Caesarean Section with Phenylephrine Versus Mephentermine - A Comparative Study.

Aim: The purpose of this study was to compare the efficacy of bolus dose of Phenylephrine Versus Mephentermine for hypotension correction in patients undergoing elective caesarean section surgery. Methodology: After obtaining approval from the ethical committee and obtaining informed consent, 60 parturients aged between 18 - 40 years of age and gestational age from 34 to 40 weeks posted for elective lower segment cesarean section were included. They were randomly divided into Group P (n=30) and Group M (n=30). The parameters observed were level of Anaesthesia, hemodynamic variables, number of doses required to correct hypotension and adverse effects. Results: A total of 60 patients were analyzed. Within 5 minutes of Spinal anaesthesia there was no significant difference between Group-P and Group-M on drop of average Systolic blood pressure, Diastolic blood pressure and average Heart rates at different minutes. But after administering the drug for hypotention correction Group P shows very high average SBP and DBP correction compared to Group M which is statistically significant (p<0.0001) and Group P shows a fall in the heart rate compared to Group M which is statistically significant (p<0.0001). Conclusion: Phenylephrine is observed to be hemodynamically more suitable than Mephentermine in patients undergoing elective caesarean section surgery. [ABSTRACT FROM AUTHOR]