A Concise Account of Synthetic Approaches to 1,2,3-Triazoles.

The article provides a comprehensive overview of various synthetic approaches to 1,2,3-triazoles, focusing on up-to-date procedures from 2000 to 2023. The significance of 1,2,3-triazoles in pharmaceuticals and their diverse applications in different fields is highlighted. The text covers classical methods as well as modern approaches, including Cu-catalyzed cycloaddition reactions and metal-free methods, under microwave, ultrasound, and continuous flow conditions. The review emphasizes the importance of click chemistry in simplifying and enhancing the synthesis of 1,2,3-triazoles for future molecular diversity explorations. [Extracted from the article]