Access to (E)- N ′-benzylidene- N -(2-(phenylsulfonyl)ethyl)acetohydrazide via C(sp 2)−H activation and reduction of (E)- N ′-benzylideneacetohydrazide with (vinylsulfonyl)benzene.

A novel route for C(sp3)-N bond formation via C(sp2)−H activation/reduction by metal-free which uses (E)- N ′-benzylideneacetohydrazide and (vinylsulfonyl)benzene to synthesize derivatives of (E)- N ′-benzylidene- N -(2-(phenylsulfonyl)ethyl)acetohydrazide has been reported. This methodology features good functional group tolerance and convenient operation. In addition, it uses inexpensive and insensitive chemical reagents as raw materials and provides an atom- and efficient method for the preparation of (E)- N ′-benzylidene- N -(2-(phenylsulfonyl)ethyl)acetohydrazides. [ABSTRACT FROM AUTHOR]