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vSPACE: exploring virtual spatial representation of articular chondrocytes at the single-cell level.

Authors :
Zhang, Chenyu
Wang, Honglin
Chung, Yeonsoo
Hong, Seung-Hyun
Olmer, Merissa
Swahn, Hannah
Lotz, Martin
Maye, Peter
Rowe, David
Shin, Dong-Guk
Source :
Bioinformatics. Oct2024, Vol. 40 Issue 10, p1-5. 5p.
Publication Year :
2024

Abstract

Summary vSPACE is a web-based application presenting a spatial representation of scRNAseq data obtained from human articular cartilage by emulating the concept of spatial transcriptomics technology, but virtually. This virtual 2D plot presentation of human articular cartage cells generates several zonal distribution patterns, for one or multiple genes at a time, revealing patterns that scientists can appreciate as imputed spatial distribution patterns along the zonal axis. Availability and implementation vSPACE is implemented in Python Dash as a web-based toolbox designed for data visualization of zonal gene expression patterns in articular cartilage chondrocytes. This tool is freely accessible at: https://vspace.cse.uconn.edu/ The source code and extra materials for this service can be downloaded from: https://github.com/zhacheny/vSPACE [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13674803
Volume :
40
Issue :
10
Database :
Academic Search Index
Journal :
Bioinformatics
Publication Type :
Academic Journal
Accession number :
180626005
Full Text :
https://doi.org/10.1093/bioinformatics/btae568