Monoamine oxidase inhibitors in depression treatment: Addressing gaps and future directions.

The article in Acta Psychiatrica Scandinavica discusses the efficacy and tolerability of monoamine oxidase inhibitors (MAOIs) in treating depressive episodes in mood disorders. While the review found similar efficacy between MAOIs and other antidepressants, previous studies suggest potential superiority of MAOIs in certain patient subgroups. The article highlights the need for further research on MAOIs in atypical depression and treatment-resistant depression (TRD), as well as exploring barriers to their use in clinical practice. Overall, the meta-analysis emphasizes the importance of continued research to optimize the use of MAOIs in depression treatment. [Extracted from the article]