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Radiotherapy in cutaneous lymphomas: Recommendations from the EORTC cutaneous lymphoma tumour group.

Authors :
Elsayad, Khaled
Guenova, Emmanuella
Assaf, Chalid
Nicolay, Jan P.
Trautinger, Franz
Stadler, Rudolf
Waldstein, Cora
Boterberg, Tom
Meijnders, Paul
Kirova, Youlia
Dobos, Gabor
Duque-Santana, Victor
Riggenbach, Elena
Elsheshtawy, Wael
Niezink, Anne
Papadavid, Evangelia
Scarisbrick, Julia
Vermeer, Maarten
Neelis, Karen J.
Bagot, Martine
Source :
European Journal of Cancer. Nov2024, Vol. 212, pN.PAG-N.PAG. 1p.
Publication Year :
2024

Abstract

The number of primary cutaneous lymphoma patients receiving low-dose radiotherapy is increasing, though controlled clinical trials defining the standard radiation dose for each specific entity have not yet been completed. Radiation oncologists are left with making highly individualized decisions that would be better enriched by additional clinical evidence. In this expert opinion, we aim to provide a clear recommendation to improve the current practice of radiation oncology. In addition, existing literature has been reviewed to develop recommendations for all types of primary cutaneous lymphoma. A prospective trial is urgently needed to identify the factors influencing patient outcomes following different radiation doses. • Reduced-dose RT is highly effective for patients with indolent types. • RT enhances the QoL in many patients with primary cutaneous lymphoma. • Radiation doses for primary cutaneous DLBCL range between 16 to 40 Gy. • There is still room for improvement in treating patients with cutaneous lymphoma. • The EORTC-CLTG provides radiotherapy dose recommendations to avoid overtreatment. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09598049
Volume :
212
Database :
Academic Search Index
Journal :
European Journal of Cancer
Publication Type :
Academic Journal
Accession number :
180584326
Full Text :
https://doi.org/10.1016/j.ejca.2024.115064