Évolution des bonnes pratiques en assistance médicale à la procréation : nouvelles règles et gestion des risques viraux.

The rules of good practice in French Assisted Reproduction Technologies (ARTs) aim to ensure the quality and safety of care. These rules, which are mandatory for all ARTs facilities, include measures to prevent the transmission of pathogens and guarantee the safety of patients and practitioners. They evolve with the current state of knowledge, which is why the decrees governing these practices are regularly revised. ARTs including artificial insemination, conventional in vitro fertilization or Intra-cytoplasmic sperm injection (ICSI), gamete storage, gamete donation and embryo transfer, are evolving in the same direction of scientific and regulatory advances. The revision of the decree of October 5, 2023, following the new bioethics law of 2021, introduces major changes, notably the abolition of the specific "viral risk" circuit and the narrowing of mandatory medical biology examinations that initially aims to minimize transmission risks. However, it maintains strict sanitary safety measures to prevent horizontal and vertical transmission, as well as transmission to health-care workers. Good laboratory practice is a common minimum standard that all ARTs' facilities must adhere to. However, laboratories are free to develop their own protocols in line with the decrees, and to carry out additional biological tests to optimize patient care. Learned societies, such as the European Society for Human Reproduction and Embryology (ESHRE), offer specific recommendations for handling gametes from patients infected with agents such as HBV, HCV, HIV, HPV, Zika and SARS-CoV-2. Good laboratory practices for ARTS, which arecontinuously reviewed, ensure a high level of quality and safety. Recent epidemics have underlined the importance of these measures in adapting rapidly to health emergencies, highlighting their necessity for dealing with the threat of new outbreaks of emerging agents. [ABSTRACT FROM AUTHOR]