POU6F2, a novel fusion partner of NUP98 in acute myeloid leukaemia: A case report.

The article in the British Journal of Haematology discusses a case report of a 61-year-old male with acute myeloid leukaemia (AML) who was found to have a gene fusion between NUP98 and POU6F2. This fusion is the first documented instance of POU6F2 involvement in a haematological malignancy, making it the second known occurrence within the POU family of transcription factors. The study highlights the importance of identifying and studying cases with genetic changes like these to better understand their impact on disease prognosis and treatment in AML. [Extracted from the article]