Adult‐Onset Parkinsonism as Late Manifestation of HIVEP2‐Associated Developmental Disorder.

A study published in Movement Disorders Clinical Practice discusses a case of adult-onset parkinsonism as a late manifestation of HIVEP2-associated developmental disorder. The patient, a 57-year-old male, presented with gait disturbances, balance difficulties, and tremor of the lower limbs. Genetic investigation revealed a loss-of-function variant in the HIVEP2 gene, which has been linked to intellectual developmental disorder. The study suggests that neurodevelopmental genes may play a role in late-onset movement disorders and highlights the importance of genetic testing and long-term outcomes assessment in individuals with neurodevelopmental disorders. [Extracted from the article]