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Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report.

Authors :
DE ASSIS, TABATA CAROLINA FARIA NASCIMENTO
RAPATONI, LIANE
SEGATO, FLAVIO NOGUEIRA
PONTES, BARBHARA THAIS MACIEL
MUGLIA, VALDAIR FRANCISCO
NETO, MIGUEL MOYSES
ROMAO, ELEN ALMEIDA
Source :
Oncology Letters. Nov2024, Vol. 28 Issue 5, p1-5. 5p.
Publication Year :
2024

Abstract

Collecting duct carcinoma (CDC) is a rare disease associated with a high mortality rate. The present study describes the case of a recipient of a kidney transplant with metastatic allograft CDC whose treatment was successful. The patient underwent nephrectomy, and chemotherapy with gemcitabine and cisplatin, while undergoing haemodialysis treatment and remained in remission after 6 years of follow-up. There is a lack of information about the treatment and clinical management of CDC; however, the combination of gemcitabine and cisplatin remains as first-line therapy. The challenge of this case was integrating chemotherapy sessions with dialysis therapy to maintain the effectiveness, tolerability and safety of the oncological treatment. In the present case report, the success of chemotherapy with gemcitabine and cisplatin was demonstrated in a metastatic renal allograft CDC in a patient with end-stage renal disease, with few side effects and no recurrence of the disease 6 years after the end of treatment. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17921074
Volume :
28
Issue :
5
Database :
Academic Search Index
Journal :
Oncology Letters
Publication Type :
Academic Journal
Accession number :
180068262
Full Text :
https://doi.org/10.3892/ol.2024.14661