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Impact and effectiveness of meningococcal C conjugate vaccine following its introduction in Spain
- Source :
-
Vaccine . Jul2005, Vol. 23 Issue 32, p4097-4100. 4p. - Publication Year :
- 2005
-
Abstract
- Abstract: This study describes the epidemiological impact of meningococcal C conjugate vaccine on age groups targeted by this vaccination programme in Spain, and estimates high short-term vaccine effectiveness values under field conditions in the 4 years following its introduction. Meningococcal C conjugate vaccine has led to a substantial reduction in incidence of meningococcal serogroup C disease in Spain among age groups targeted for intervention nationwide. Disease surveillance in the 4 years since the vaccine was introduced has enabled vaccine effectiveness (VE) to be estimated. The vaccine registered high short-term VE values but there has been some loss of VE with time. Four years after vaccination, vaccine protection levels exceeded 94% in cohorts immunised during the campaign. Among children vaccinated in routine childhood immunisation programmes, however, long-term VE loss was greater. Accordingly, there is a need for ongoing re-evaluation of VE and ascertainment of long-term vaccine protection. The findings reported would allow to decide on the advisability of revising current vaccination guidelines. [Copyright &y& Elsevier]
- Subjects :
- *VACCINATION
*VACCINES
*EPIDEMIOLOGY
*PREVENTIVE medicine
Subjects
Details
- Language :
- English
- ISSN :
- 0264410X
- Volume :
- 23
- Issue :
- 32
- Database :
- Academic Search Index
- Journal :
- Vaccine
- Publication Type :
- Academic Journal
- Accession number :
- 18006321
- Full Text :
- https://doi.org/10.1016/j.vaccine.2005.03.045