益生菌发酵中草药对断奶仔猪生长性能、 血清免疫指标、抗氧化能力及肠道功能的影响

The experiment aimed to study the effects of probiotic-fermented Chinese herbal medicine on the growth performance, serum immune indexes, antioxidant capacity, and intestinal function of weaned piglets. A total of 54 healthy weaned piglets, aged 35 days and weighing (8.76±0.54) kg, were selected, half in male and female, randomly divided into three treatment groups, with three replicates in each group and six piglets in each replicate. The control group was fed a basal diet, while the experimental group A and group B were supplemented with 0.5% and 1.0% of probiotic-fermented Chinese herbal medicine in the basal diet, respectively. The trial period was 28 days. The results showed that compared to the Chinese herbal medicine before fermentation, the total flavonoids, total alkaloids, total saponins, and crude polysaccharides in the probiotic-fermented Chinese herbal medicine significantly increased (P<0.05). Compared to the control group, the average daily weight gain significantly increased (P<0.05), and the feed conversion ratio and diarrhea rate significantly decreased in group A and group B (P<0.05). The levels of immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM), complement C3, and complement C4 in the serum were significantly higher in group A and group B than in the control group (P<0.05). The total antioxidant capacity (T-AOC), and the activities of total superoxide dismutase (T-SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) in the serum of piglets in group A and group B were significantly increased (P<0.05), while the concentration of malondialdehyde (MDA) in the serum was significantly reduced (P<0.05). The levels of Lactobacillus and yeast in the small intestine of group A and group B significantly increased (P<0.05), while E. coli and Salmonella significantly decreased (P<0.05). The villus height and villus-to-crypt ratio (V/C) in the duodenum, jejunum, and ileum of group A and group B significantly increased (P<0.05), and the crypt depth in the jejunum significantly decreased (P<0.05). The study indicates that the addition of probiotic-fermented Chinese herbal medicine to the diet improves the growth performance, immune function, antioxidant capacity, and intestinal function of weaned piglets, and the effect of 0.5% probiotic-fermented Chinese herbal medicine is better. [ABSTRACT FROM AUTHOR]