Multiple drugs: Various toxicities: 3 case reports.

This article describes three case reports of patients, including two boys and one girl, who experienced lack of efficacy or adverse reactions to various medications. The first case involved a 14-year-old boy who initially received carbamazepine for complex partial seizures but developed Stevens-Johnson syndrome. He was later diagnosed with ADHD and OCD and experienced worsened movements and agitation with atomoxetine, fluoxetine, and risperidone. The second case involved a 10-year-old boy with an obsessive-compulsive spectrum disorder who did not respond to fluoxetine and developed increased tics. The third case involved a 16-year-old girl with Tourette syndrome who experienced worsening mood disturbances and tics with risperidone and sodium valproate. Adjustments to their medications and additional therapies were made to manage their conditions. [Extracted from the article]