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3-((2-(4-Chloro-5-ethoxy-2-nitrophenoxy)acetamido)methyl)phenyl-dimethylcarbamate.

Authors :
Leuci, Rosalba
Dininno, Daniela
Paparella, Marco
Piemontese, Luca
Source :
Molbank. Sep2024, Vol. 2024 Issue 3, pM1863. 5p.
Publication Year :
2024

Abstract

In this study, we report the synthesis of 3-((2-(4-chloro-5-ethoxy-2-nitrophenoxy)acetamido)methyl)phenyl-dimethylcarbamate, designed on the basis of the structures of the commercial acetylcholinesterase inhibitor drug rivastigmine and a substituted aryloxyacetic acid, aiming at a multi-target approach to the therapy of Alzheimer's disease. The hybrid was obtained thanks to a synthesized intermediate by-product. The compound was fully characterized by using 1H and 13C NMR, FT-IR and HRMS. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14228599
Volume :
2024
Issue :
3
Database :
Academic Search Index
Journal :
Molbank
Publication Type :
Academic Journal
Accession number :
179967985
Full Text :
https://doi.org/10.3390/M1863