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3-((2-(4-Chloro-5-ethoxy-2-nitrophenoxy)acetamido)methyl)phenyl-dimethylcarbamate.
- Source :
-
Molbank . Sep2024, Vol. 2024 Issue 3, pM1863. 5p. - Publication Year :
- 2024
-
Abstract
- In this study, we report the synthesis of 3-((2-(4-chloro-5-ethoxy-2-nitrophenoxy)acetamido)methyl)phenyl-dimethylcarbamate, designed on the basis of the structures of the commercial acetylcholinesterase inhibitor drug rivastigmine and a substituted aryloxyacetic acid, aiming at a multi-target approach to the therapy of Alzheimer's disease. The hybrid was obtained thanks to a synthesized intermediate by-product. The compound was fully characterized by using 1H and 13C NMR, FT-IR and HRMS. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ALZHEIMER'S disease
*ACETYLCHOLINESTERASE inhibitors
*RIVASTIGMINE
Subjects
Details
- Language :
- English
- ISSN :
- 14228599
- Volume :
- 2024
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Molbank
- Publication Type :
- Academic Journal
- Accession number :
- 179967985
- Full Text :
- https://doi.org/10.3390/M1863