Brain tumefactive vasculitis in primary Sjögren syndrome.

This article discusses a case of tumefactive vasculitis in a 74-year-old woman with primary Sjögren syndrome (SS). The patient presented with a headache and experienced reduced consciousness and seizures. Brain magnetic resonance imaging (MRI) revealed an expansive lesion in the right frontal lobe, along with perivascular enhancement in the right basal ganglia. Histopathological analysis confirmed the presence of vasculitis. The patient was treated with immunoglobulin therapy, methylprednisolone, and rituximab, resulting in complete improvement of neurological symptoms. Tumefactive vasculitis should be considered as a differential diagnosis for expansive brain lesions in patients with primary SS. [Extracted from the article]