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Isolated cerebellar stroke in a paediatric patient with typical haemolytic uraemic syndrome: a case report and literature review.

Authors :
Lo Bianco, Manuela
Rinella, Sergio
D'Arco, Felice
Ioannidou, Evangelia
Kaliakatsos, Marios
Source :
Neuroradiology. Oct2024, Vol. 66 Issue 10, p1859-1865. 7p.
Publication Year :
2024

Abstract

Haemolytic Uraemic Syndrome (HUS) is a rare medical condition characterised by microangiopathic haemolytic anaemia, thrombocytopenia, and acute kidney injury. Neurological complications are documented but rarely involve the cerebellum. We present a unique case of a 23-month-old male with HUS triggered by Escherichia coli-O157 (E.coli-O157) infection leading to an isolated cerebellar stroke. The patient initially presented with fever, bloody stools, and seizures. Confirmation of E.coli-O157 infection was obtained, and MRI revealed an isolated cerebellar stroke. Treatment included supportive care, anticoagulation for a right atrial thrombus, with gradual improvement observed. This case highlights the unusual occurrence of isolated cerebellar stroke in HUS patients, emphasising the importance of promptly recognizing manifestations of the central nervous system and the necessity for a multidisciplinary approach. Finally, a comprehensive literature review was conducted to identify cases of HUS patients with cerebellar involvement. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00283940
Volume :
66
Issue :
10
Database :
Academic Search Index
Journal :
Neuroradiology
Publication Type :
Academic Journal
Accession number :
179873453
Full Text :
https://doi.org/10.1007/s00234-024-03407-x