Effectiveness of Intradialytic Exercise in Improving Muscle Strength and Physical Function for Patients Undergoing Hemodialysis: A Systematic Review.

Introduction: Chronic kidney disease (CKD), which progresses to end-stage renal disease (ESRD) is cause the sixth-leading of death worldwide. Patients with ESRD receiving hemodialysis (HD) typically engage in low levels of physical activity, which is linked to higher rates of morbidity and mortality. Aim: of This systematic review analyzes the efficacy of Intra Dialytic Exercise (IDE) as intervention for end-stage renal disease patients, to increase physical function, mobility, and decreased levels of dependency. Design: The scope of the review covers full-text articles published between December 2019 to April 2023 on data base: PubMed, EBSCO, Wiley, Science direct, ProQuest, Web of Science, Springer. The review was conducted following the PRISMA guideline statement based on PICO (Population, Intervention, Comparison, Outcome). To determine which study to include in the analysis, a set of criteria were applied, including requiring that the study includes adult ESRD patients has received at least 3 months of hemodialysis. The review article was assessed using the JBI critical appraisal tool. Results: A total of 30 studies were selected from more than 900 articles but only 11 randomized controlled trial (RCT) studies are included in this systematic review. IDE shown significantly to improve physical function, increase muscular strength, improve quality of life (QoL). Conclusion: IDE practiced in Renal Unit were shown to have significant positive effect on physical function, increase muscles strength, and improve QoL. There is a lack of the types, modality of exercises investigated, therefore data was limited for several outcomes. [ABSTRACT FROM AUTHOR]