PODBoost: an explainable AI model for polycystic ovarian syndrome detection using grey wolf-based feature selection approach.

Polycystic Ovary Syndrome (PCOS) is a recurring endocrine disorder that primarily affects women of reproductive age. It is difficult to diagnose due to its heterogeneous characteristics and overlapping symptoms with other illnesses. As a result, accurate and trustworthy prediction models are required to detect PCOS early. This research work aims to develop ML methods that predict the risk of PCOS among women based on demographic and clinical features. The entire framework is divided into four phases: in Phase I of the study, the SMOTE-Tomek Links (SMTL) technique balances the data set by combining oversampling and undersampling approaches. A novel meta-heuristic-based feature selection approach, the Grey Wolf Optimization (GWO) method, has been employed to select the most crucial features from the dataset, explained in Phase II. Subsequently, in Phase III, a hybridized classifier PODBoost algorithm (Polycystic Ovarian Disorder Boosting algorithm) is devised for faithful early prediction of PCOS using the concepts of different classical supervised learning algorithms. Finally, Explainable AI (XAI) such as the Local Interpretable Model-Agnostic Explanations (LIME) tool has been implemented to interpret relevant predictions made by the proposed classifier. The proposed algorithm is examined utilizing numerous metrics such as Accuracy, Error-Rate, ROC-AUC Score, Recall, Precision, and F1-Score. Among all the evaluated models, the proposed hybridized model has shown an impressive performance with an exceptional accuracy of 97.42 % , indicating its superiority by delivering outstanding results. Based on the findings, the novel meta-heuristic-based feature selection method significantly impacts the outcomes of the proposed hybridized PODBoost algorithm. This algorithm may be recommended to predict PCOS or other relevant diseases having datasets which are multimodal in nature. [ABSTRACT FROM AUTHOR]