Quantitative evaluation of breast lesions using ultrafast MRI has come so far.

Ultrafast dynamic contrast-enhanced (UF-DCE) MRI has become a widely accepted sequence in breast MRI over the past decade. UF-DCE MRI allows for the detailed evaluation of breast lesion enhancement by completing multiple imaging phases within 1-2 minutes. Parameters such as maximum slope (MS) and time to enhancement (TTE) have been introduced to evaluate the initial time-intensity curve (TIC) from UF-DCE images. A systematic review of 16 studies analyzing 2090 lesions found that UF-DCE MRI-derived kinetic parameters had a pooled sensitivity of 83% and specificity of 77% for differentiating benign from malignant breast lesions. The review also found that MS and TTE parameters showed no significant difference in their ability to discriminate between malignant and benign lesions. The heterogeneity among studies may be due to various factors, and further standardization may be needed to apply universal cut-off values. The authors suggest that the kinetic information from UF-DCE MRI could be aggregated into parameters that are highly versatile and have few differences among radiologists. They also propose dividing dynamic parameters into three groups rather than using a single cut-off value. Overall, UF-DCE MRI shows promise in the quantitative evaluation of breast lesions, but further research and standardization are needed. [Extracted from the article]