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STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells.

Authors :
Joo Eun Jung
Hyun Gyu Lee
Ik Hyun Cho
Doo Hyun Chung
Sun-Hee Yoon
Young Mok Yang
Jung Weon Lee
Seongwon Choi
Jong-Wan Park
Sang-Kyu Ye
Myung-Hee Chung
Source :
FASEB Journal. Aug2005, Vol. 19 Issue 10, p1296-1298. 3p. 2 Diagrams, 1 Graph.
Publication Year :
2005

Abstract

Presents a study on the effect of STAT3 on hypoxia-inducible factor-1 (HIF-1)-mediated vascular endothelial factor gene expression in human renal carcinoma cells. Activation of STAT3 by hypoxia; Relationship between HIF-1α and STAT3; Result of the coimmunoprecipitation assays.

Details

Language :
English
ISSN :
08926638
Volume :
19
Issue :
10
Database :
Academic Search Index
Journal :
FASEB Journal
Publication Type :
Academic Journal
Accession number :
17959056
Full Text :
https://doi.org/10.1096/fj.04-3099fje