Primary Mucinous lesions of Appendix: A Case series.

Background Primary neoplasms of the appendix are rare, present in less than 2% of surgical appendectomies. They are frequently misinterpreted in histopathological examination due to their relative rarity. This study focuses on understanding the disease burden of appendiceal mucinous lesions in our tertiary centre. Methods A retrospective analysis of all non neoplastic and neoplastic mucinous lesions in appendicectomy specimens were done from January 2021 to May 2024, which were received in the Department of Pathology in our tertiary care center at Wayanad. All the specimens and slides available were retrieved from the archives. The clinical presentation, radiological findings, gross and microscopic findings were collected from the HIS (Hospital Information System) and records available in the Department of pathology. Results From the 3 years and 5 months data of all appendicectomy specimens, 7 cases of mucinous appendiceal lesions were identified. 4 out of these were non neoplastic, simple mucocele. Almost all of which were clinically diagnosed as acute appendicitis. 2 cases were LAMN (Low Grade Mucinous Appendiceal Neoplasm) and 1 was HAMN (High Grade Mucinous Appendiceal Neoplasm). Conclusion Mucinous neoplasms of appendix are rare tumours with challenging clinical management. Staging of LAMN and high grade tumours is necessary to determine treatment options and prognosis. Mucoceles and Low‐grade tumours may be surgically treated while high‐grade tumours may require other options including debulking surgery and chemotherapy. [ABSTRACT FROM AUTHOR]