Mortality and Cardiovascular disease burden of uncontrolled Diabetes in a registry-based cohort study.

Background: The present study was conducted for evaluating the efficacy of Intrathecal levobupivacaine and bupivacaine among patients undergoing inguinal hernia surgery under spinal anesthesia. Materials & methods: A total of 50 patients were enrolled and were randomized into two study groups as follows: Group 1- intrathecal isobaric levobupivacaine, and Group 2- intrathecal hyperbaric racemic bupivacaine. Complete demographic and clinical details of all the patients was obtained. Anthropometric examination of all the patients was done. Patients having history of any systemic illness, or any known drug allergy were excluded. Complete baseline hemodynamic and biochemical profile at baseline was evaluated. All the patients underwent type of spinal according to their respective study groups. Quality of anesthesia was assessed. Motor and sensory block characteristics were also evaluated. All the results were recorded in Microsoft excel sheet and were subjected to statistical analysis using SPSS software. Results: Mean age of the patients of the group 1 and group 2 was 43.8 years and 45.1 years respectively. Majority proportion of patients of both the study groups were males. Among patients of group 1, excellent and satisfactory anesthesia was seen in 84 percent and 16 percent of the patients respectively. Among patients of group 2, excellent and satisfactory anesthesia was seen in 88 percent and 12 percent of the patients respectively. Mean onset of sensory and motor block were similar for both the study groups. However; mean duration of motor block was significantly lower in group 1 (176.3 mins) in comparison to group 2 (191.7 mins). Conclusion: Levobupivacaine offered high quality of anesthesia among patients having spinal anesthesia with shorter duration of motor block, allowing quicker recovery. [ABSTRACT FROM AUTHOR]