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Low‐energy differential target multiplexed SCS derivative reduces pain and improves quality of life through 12 months in patients with chronic back and/or leg pain.

Authors :
Peacock, Jeffery
Provenzano, David
Fishman, Michael
Amirdelfan, Kasra
Bromberg, Todd
Schmidt, Todd
White, Thomas
Grewal, Prabhdeep
Justiz, Rafael
Calodney, Aaron
El‐Naggar, Amr
Shah, Binit
Esposito, Michael
Gatzinsky, Kliment
Kallewaard, Jan Willem
Poree, Lawrence
Cleland, Andrew
Rice, Calysta
Theis, Erin
Noel, Kate
Source :
Pain Practice. Sep2024, p1. 13p. 8 Illustrations.
Publication Year :
2024

Abstract

Introduction Methods Results Conclusion Energy‐reducing spinal cord stimulation (SCS) approaches have the potential to impact patient experience with rechargeable and non‐rechargeable SCS devices through reducing device recharge time or enhancing device longevity. This prospective, multi‐center study evaluated the safety, effectiveness, and actual energy usage of differential target multiplexed (DTM) endurance therapy, a reduced energy DTM SCS derivative.Subjects who reported an overall pain visual analog score (VAS) of ≥6/10 cm and an Oswestry Disability Index score of 21–80 out of 100 at baseline with moderate to severe chronic, intractable back and/or leg pain were eligible. Evaluation visits occurred at 1, 3, 6, and 12 months post‐device activation. The primary objective was to characterize change in overall pain intensity, as measured by VAS, from baseline to 3‐month visit.Fifty‐seven subjects enrolled at 12 US sites from November 2020 through June 2021, 35 were implanted with a rechargeable SCS device, and 27 completed the 12‐month visit. Subjects experienced a 50.4% mean reduction in overall pain from baseline at the 3‐month follow‐up that was sustained through 12 months. Additional outcomes including changes in overall, back, and leg pain intensity, quality of life, disability, therapy satisfaction, safety, and current battery usage are shown through 12‐month follow‐up.The use of DTM endurance SCS therapy in this study resulted in reductions in pain relief through 12 months, demonstrating that energy‐reducing stimulation patterns can provide clinical benefit. Clinically effective, reduced energy SCS derivatives have the potential to impact patient experience through either reduced recharge requirements or increased device longevity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
15307085
Database :
Academic Search Index
Journal :
Pain Practice
Publication Type :
Academic Journal
Accession number :
179569985
Full Text :
https://doi.org/10.1111/papr.13407