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Relationship between short- and long-term memory and short- and long-term extinction
- Source :
-
Neurobiology of Learning & Memory . Jul2005, Vol. 84 Issue 1, p25-32. 8p. - Publication Year :
- 2005
-
Abstract
- Abstract: Both the acquisition and the extinction of memories leave short- and long-term mnemonic traces. Here, we show that in male Wistar rats, the short-term memory for a step-down inhibitory avoidance task (IA) is resistant to extinction, and that its expression does not influence retrieval or extinction of long-term memory. It has been known for some time that short- and long-term inhibitory avoidance memory involve separate and parallel processes. Here we show that, instead, short-term extinction of IA long-term memory is the first step towards its long-term extinction, and that this link requires functional NMDA receptors and protein synthesis in the CA1 region of the dorsal hippocampus at the time of the first CS-no US presentation. [Copyright &y& Elsevier]
- Subjects :
- *SHORT-term memory
*RATS
*LEARNING
*PROTEIN synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 10747427
- Volume :
- 84
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Neurobiology of Learning & Memory
- Publication Type :
- Academic Journal
- Accession number :
- 17954757
- Full Text :
- https://doi.org/10.1016/j.nlm.2005.03.002