Reversal of Benzodiazepine-Induced Myoclonus by Flumazenil in the Neonatal Intensive Care Unit.

This article, published in the journal Neuropediatrics, discusses a case study of a late preterm baby who experienced myoclonus (involuntary muscle jerks) after being given lorazepam, a benzodiazepine sedative, in the neonatal intensive care unit. The myoclonus did not respond to phenobarbital treatment, but it ceased after the administration of flumazenil, a medication used to reverse the effects of benzodiazepines. The article suggests that benzodiazepine-induced myoclonus may be more common in preterm infants due to the developmental activity of the GABA receptor. The case study provides videographic documentation to enhance understanding of this phenomenon. [Extracted from the article]