孕期被动吸烟对1岁儿童神经行为发育异常的影响.

Objective To explore the impact of passive smoking during pregnancy on neurobehavioral developmental abnormalities in 1 - year - old children. Methods 1 363 pairs of mothers and children from the Shenzhen birth Cohort study platform were selected as the research objects. Questionnaire was used to investigate the general demography characteristics and passive smoking of pregnant women during pregnancy, and the age and development process questionnaire (ASQ - 3/ASQ: SE) was used to assess the neurobehavioral development of children at one year old. Analyze the impact of passive smoking during pregnancy on neurobehavioral developmental abnormalities in 1 - year - old children using a logistic regression model. Results Passive smoking during pregnancy had varying degrees of harmful effects on the development of 1 - year - old children, except for gross movements. Compared with those without passive smoking, pregnant women with severe passive smoking in early pregnancy had an increased risk of delayed development in communication (OR - 1. 932, 95% Cf: 1. 023 - 3. 648), fine motor skills (OR = 3. 388, 95% CI: 1. 232 - 9. 317), problem - solving (OR = 3. 270, 95% CI: 1. 317 - 7.795), and social emotional development (OR = 1.792, 95% CI: 1. 159 - 2.772) among their offspring. In mid - pregnancy, pregnant women who smoke passively had an increased risk of delayed development in communication (OR = 1, 802, 95%CI: 1.068 -3.039) and personal social (OR = 1.705, 95% CI: 1.080 -2.837) among their offsprings while pregnant women who smoke heavily had an increased risk of delayed development in communication (OR = 2. 864, 95% CI: 1.322-6.240) and social emotional (OR = 1.882, 95% CI: 1. 081 - 3.275) among their offspring. In late pregnancy, pregnant women with severe passive smoking had an increased risk of delayed communication (OR = 3. 415, 95 % CI: 1. 366 - 3. 158), fine motor skills (OR = 3. 976 times, 95% CI: 1. 838 - 13. 360), and social emotional development (OR = 2. 231, 95% C/: 1. 234 - 4. 032) in their offspring. Conclusion Passive smoking in the early, middle, and late stages of pregnancy can have varying degrees of harmful effects on the neurobehavioral development of offspring at one year old. Suggest relevant departments to increase publicity and education efforts, guide the public to reduce indoor smoking and pay attention to maternal health and early neurobehavioral development in children. [ABSTRACT FROM AUTHOR]