基于效标法与分布法的消化性溃疡生命质量 测定量表的最小临床重要性差值制定与评估

Objective To explore the minimum clinically important difference (MCID) of peptic ulcer scale QLICD - PU (V2. 0) among the System of quality of life instruments for chronic diseases. Methods Using convenience samplings the questionnaire was administered from March 2013 to August 2014 using the QLICD - PU (V2. 0) scale, and the MCIDs were calculatedusing the anchor - based and distribution - based methods, respectively, and analyzed to compare the MCIDs developed by taking the mean, taking the minimum, and taking the maximum methods. Results The MCIDs of physical functioning (8.53), psychological functioning (8.45), social functioning (7.61), general module (7. 05), specific module (8. 82), and overall scale (7. 53) obtained by taking the mean method; the MCIDs obtained by taking the minimum method were 5. 25, 5. 78, 6. 16, 4. 19, 7. 18 and 4. 09, respectively; the MCID obtained by taking the maximum method were 11. 99, 12.05, 10.09, 9.48, 10. 99 and 11.04, respectively. Conclusion In this paper, MCID was formulated by using various methods and criteria, which can be chosen by the users according to the situation. MCID can be used to assess the clinical efficacy of patients with peptic ulcers for the application of quality of life. The MCID values formulated can be validated further by clinical practice in subsequent studies. [ABSTRACT FROM AUTHOR]