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Refinement in animal experimentation: calling time on the use of chloral hydrate for nonârecovery procedures and euthanasia.
- Source :
-
Journal of Physiology . Sep2024, Vol. 602 Issue 17, p4077-4078. 2p. - Publication Year :
- 2024
-
Abstract
- The author criticizes the use of chloral hydrate for refinement in animal experimentation and euthanasia. He explains the principles of replacement, reduction and refinement that provide an ethical framework for the use of research animals and improving their welfare. He describes factors behind the continued use of chloride hydrate as a sedative, hypnotic or anaesthetic agent. He discusses reasons for its unethical use for euthanasia and the availability of more refined choices.
Details
- Language :
- English
- ISSN :
- 00223751
- Volume :
- 602
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- Journal of Physiology
- Publication Type :
- Academic Journal
- Accession number :
- 179375634
- Full Text :
- https://doi.org/10.1113/JP286687