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A New Cyclic Peptide from Betel Nut Endophytic Fungus Alternaria sp. RW-AL.

Authors :
Ruan, Wu
Ma, Qing-Yun
Guo, Jiao-Cen
Xie, Qing-Yi
Yang, Li
Dai, Hao-Fu
Wu, You-Geng
Zhao, You-Xing
Source :
Chemistry of Natural Compounds. Jul2024, Vol. 60 Issue 4, p693-696. 4p.
Publication Year :
2024

Abstract

A new cyclic peptide alternarin A (1), along with seven known compounds, alternariol (2), sulfated derivative of alternariol (3), alternariol methyl ether (4), altenuene (5), 2,5-dimethyl-7-hydroxychromone (6), diaporthein A (7), isopterocarpolone (8), were isolated from the betel nut endophytic fungus Alternaria sp. RW-AL. The structure of 1 was elucidated by 1D and 2D NMR spectra as well as HR-ESI-MS analysis. Compounds 1, 4, and 5 showed definite antibacterial activities against Staphylococcus aureus ATCC 6538 and Bacillus subtilis ATCC 6633. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00093130
Volume :
60
Issue :
4
Database :
Academic Search Index
Journal :
Chemistry of Natural Compounds
Publication Type :
Academic Journal
Accession number :
179325910
Full Text :
https://doi.org/10.1007/s10600-024-04413-4