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Unveiling the Therapeutic Potential of Quinazolinone Derivatives in Cancer Treatment: A Comprehensive Exploration.

Authors :
Kaur, Jasneet
Kaur, Sukhmeet
Muskan
Kaur, Navneet
Kumar, Vipan
Anand, Amit
Source :
ChemistrySelect. 8/27/2024, Vol. 9 Issue 32, p1-24. 24p.
Publication Year :
2024

Abstract

Quinazolinone derivatives have garnered attention for their diverse biological activities, including anticancer properties. This review combines findings from 2018 to 2024, focusing on the impact of quinazolinones on cancer cells, tubulin formation, and EGFR/PI3 K pathways. By unraveling the intricacies of structure‐activity relationships, this review endeavors to provide guidance for researchers in identifying promising avenues for the development of cancer treatments. Although in vitro studies underscore significant potential, it is imperative that future research prioritizes pre‐clinical investigations to seamlessly traverse the transitional phase towards clinical applications, thereby propelling the advancement of quinazolinone‐based cancer therapy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23656549
Volume :
9
Issue :
32
Database :
Academic Search Index
Journal :
ChemistrySelect
Publication Type :
Academic Journal
Accession number :
179280241
Full Text :
https://doi.org/10.1002/slct.202401366